AACR Annual Meeting 2023
Abstract 1628: "A small-molecule inhibitor of WRN selectively kills MSI-H cancer cells and phenocopies WRN genetic defects"
Abstract 1644: "Dual inhibition of MAT2A and PRMT5 delivers synergistic anti-tumor responses in preclinical models of MTAP-deleted cancer" (Fischer, M. et al.)
Abstract 1637: "MAT2A inhibition in MTAP-/- tumors confers mechanistic vulnerabilities to multiple clinically actionable synthetic lethal drug combinations" (Gerrick, K. et al.)
Abstract 6093: "IDE161, a potential first-in-class clinical candidate PARG inhibitor, selectively targets Homologous-Recombination-Deficient and PARP inhibitor resistant breast and ovarian tumors" (Abed, M. et al.)
